Functional Insights into Protein Kinase A (PKA) Signaling from C. elegans
Protein kinase A (PKA), which regulates a diverse set of biological functions downstream of cyclic AMP (cAMP), is a tetramer consisting of two catalytic subunits (PKA-C) and two regulatory subunits (PKA-R).When cAMP binds tonic shower cap the PKA-R subunits, the PKA-C subunits are released and interact with downstream effectors.In Caenorhabditis el